Sub aaa()

On Error GoTo myerr1
'Set args = wscript.Arguments
'msgbox "args.count=" & args.count
'If args.Count <> 1 Then MsgBox "need file": wscript.Quit
Dim conn As New ADODB.Connection
Set conn = New ADODB.Connection

'Set conn = CreateObject("ADODB.Connection")
connStr = "Provider=Microsoft.ACE.OLEDB.12.0; Data Source=c:\data\db.accdb;Mode=Share Deny Read|Share Deny Write;Persist Security Info=False;Jet OLEDB:Database Password=123456"
'MsgBox connStr
conn.Open connStr
conn.Execute ("ALTER DATABASE Password abcd 123456")
conn.Close
MsgBox "done"
Exit Sub




myerr1:
 MsgBox Err.Description & "aa"



End Sub

---笔记
如果CreateObject("ADODB.Connection" 执行失败。
Vba 窗口 点击菜单上的"工具">>"引用",勾选它:Microsoft ActiveX Data Objects 2.x

Microsoft.Jet.OLEDB.4.0;  --office2003
Microsoft.ACE.OLEDB.12.0;  --office2007
ALTER DATABASE PASSWORD 新密码 旧密码 
ALTER DATABASE Password new  old